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This list may not describe all possible side effects.
severe stomach area pain, especially toward your right side
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
Store at room temperature below 30 degrees C (86 degrees F). Keep in a well-closed container. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. Usually, a pharmacist must prepare this medicine into a suspension for administration to children.
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Antacids may  interfere with the absorption of ursodiol. Take ursodiol at least 1 hour before or 2 hours after an antacid dose.
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Take ursodiol capsules or tablets by mouth. Follow the directions on the prescription label. Take the capsules with food or milk to improve absorption and limit stomach or intestinal side effects. Take your doses at regular intervals. Do not take your medicine more often than directed.
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Side effects that you should report to your prescriber or health care professional as soon as possible:
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
 
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
 
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What side effects may I notice from taking ursodiol?
URSODIOL is a bile acid. The drug helps dissolve gallstones in those who cannot have gallbladder surgery or who do not need the surgery. Ursodiol may be used with a procedural device that fragments the gallstone into smaller pieces; the procedure, called lithotripsy, allows the drug to dissolve the stones more quickly. Ursodiol is also useful for certain liver diseases of adults, children and infants; the drug reduces itching and other symptoms.
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NOTE: This medicine is only for you. Do not share this medicine with others.
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Side effects that you should report to your prescriber or health care professional as soon as possible:
Antacids may  interfere with the absorption of ursodiol. Take ursodiol at least 1 hour before or 2 hours after an antacid dose.
Visit your prescriber or health care professional for regular checks on your progress. It may take months of therapy to get the right response. Your prescriber or health care professional will schedule tests to see if your gallstones are dissolving or if your liver problem is improving. Report continued or worsened nausea, vomiting, or abdominal pain to your prescriber.
 
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Continue to take your medicine even if you feel better, unless directed otherwise by your prescriber or health care professional. Do not stop taking except on your prescriber's advice.
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URSODIOL is a bile acid. The drug helps dissolve gallstones in those who cannot have gallbladder surgery or who do not need the surgery. Ursodiol may be used with a procedural device that fragments the gallstone into smaller pieces; the procedure, called lithotripsy, allows the drug to dissolve the stones more quickly. Ursodiol is also useful for certain liver diseases of adults, children and infants; the drug reduces itching and other symptoms.
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